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A fresh study exhibits which the compound conolidine, located in the pinwheel flower, only binds to at least one individual scavenger receptor."We verified that conolidine binds to the newly recognized opioid receptor ACKR3, though exhibiting no affinity for another four classical opioid receptors. By doing so, conolidine blocks ACKR3 and helps pre… Read More

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Plants have already been Traditionally a supply of analgesic alkaloids, although their pharmacological characterization is often restricted. Among this kind of normal analgesic molecules, conolidine, present in the bark in the tropical flowering shrub Tabernaemontana divaricataConolidine belongs to a bigger course of normal items, termed C5-nor ste… Read More